Frequently from a startup (not restart but from S5), all of my USB ports will not be recognized. I have a 4GB flash drive as D:, a Seagate external HDD as E: and a 64GB flash as F:, and sometimes the Seagate device does not show up. I have to restart to get it to show up. Sometimes one of the other drives will not show up. The Seagate device and the 64GB flash drive are plugged directly into the NUC while the 4GB flash (and a printer) are plugged into a powered USB replicator. I also have a Logitech receiver plugged into a USB extension plugged directly into the NUC to keep it out of the way of the electromagnetic radiation, as discussed in Intel's white paper on the matter. My OS is W7HP 64-bit and my BIOS is the January 15, 2015 version.
Do I have a defective NUC? This is a fairly replicable occurrence, although I'm not sure it occurs 100% of the time since I only power down the NUC for OS updates and such.